Amitriptyline Hcl Information
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Amitriptyline Hcl Uses
Amitriptyline hcl is used to treat symptoms of depression.
Amitriptyline hcl is in a class of medications called tricyclic antidepressants
(mood elevators). It works by increasing the amounts of certain
natural substances in the brain.
Amitriptyline Hcl Directions
Amitriptyline comes as a tablet to take by mouth. It is usually
taken one to four times a day. To help you remember to take Amitriptyline,
take it around the same time every day. Follow the directions on
your prescription label carefully, and ask your doctor or pharmacist
to explain any part you do not understand. Take Amitriptyline exactly
as directed. Do not take more or less of it or take it more often
than prescribed by your doctor. Your doctor will probably start
you on a low dose of Amitriptyline and gradually increase your dose.
It may take a few weeks or longer before you feel the full benefit
of Amitriptyline. Continue to take Amitriptyline even if you feel
well. Do not stop taking Amitriptyline without talking to your doctor.
Stopping amitriptyline suddenly may cause withdrawal symptoms (upset
stomach, headache, and lack of energy). Your doctor will probably
decrease your dose gradually.
Amitriptyline Hcl Cautions
Before taking Amitriptyline, tell your doctor and pharmacist if
you are allergic to Amitriptyline hcl or any other medications. Do not
take Amitriptyline hcl if you are taking monoamine oxidase (MAO) inhibitors,
including phenelzine (Nardil) and tranylcypromine (Parnate), or
have stopped taking them within the past 2 weeks; or if you are
taking cisapride (Propulsid). Tell your doctor and pharmacist what
other prescription and nonprescription medications, vitamins, nutritional
supplements, and herbal products you are taking.
Be sure to mention any of the following: antihistamines; cimetidine
(Tagamet); diet pills; disulfiram (Antabuse); ethchlorvynol (Placidyl);
guanethidine (Ismelin); ipratropium (Atrovent); quinidine (Quinidex);
medications for irregular heartbeats such as flecainide (Tambocor)
and propafenone (Rythmol); medications for anxiety, asthma, colds,
irritable bowel disease, mental illness, nausea, Parkinson's disease,
seizures, ulcers, or urinary problems; other antidepressants; phenobarbital
(Bellatal, Solfoton); sedatives; selective serotonin reuptake inhibitors
(SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem),
fluvoxamine (Luvox), paroxetine (Paxil), and sertraline (Zoloft);
sleeping pills; thyroid medications; and tranquilizers. Your doctor
may need to change the doses of your medications or monitor you
carefully for side effects.
Tell your doctor if you drink large amounts of alcohol; if you have
recently had a heart attack; and if you have or have ever had glaucoma;
an enlarged prostate; difficulty urinating; mental illness; seizures;
an overactive thyroid gland (hyperthyroidism); diabetes; or liver,
kidney, or heart disease. Tell your doctor if you are pregnant,
plan to become pregnant, or are breast-feeding. If you become pregnant
while taking Amitriptyline hcl, call your doctor immediately. If you
are having surgery, including dental surgery, tell the doctor or
dentist that you are taking Amitriptyline. you should know that
Amitriptyline may make you drowsy. Do not drive a car or operate
machinery until you know how amitriptyline hcl affects you. Remember
that alcohol can add to the drowsiness caused by Amitriptyline.
Possible Side Efects of Amitriptyline Hcl
Amitriptyline hcl may cause side effects. Tell your doctor if any of
these symptoms are severe or do not go away: upset stomach, vomiting,
drowsiness, weakness or tiredness, excitement or anxiety, difficulty
falling asleep or staying asleep, nightmares, restlessness, headaches,
dry mouth, constipation, difficulty urinating, blurred vision, pain,
burning, or tingling in the hands or feet, changes in sex drive
or ability, excessive sweating, changes in appetite or weight, confusion,
unsteadiness, Some side effects can be serious. The following symptoms
are uncommon, but if you experience any of them, call your doctor
immediately: slow or difficult speech; dizziness or faintness; weakness
or numbness of an arm or a leg; crushing chest pain; rapid, pounding,
or irregular heartbeat; severe skin rash or hives; swelling of the
face and tongue; yellowing of the skin or eyes; jaw, neck, and back
muscle spasms; shaking hands that you cannot control; difficulty
sitting still; fainting; unusual bleeding or bruising; seizures;
seeing things or hearing voices that do not exist (hallucinating)
. Amitriptyline hcl may cause other side effects. Call your doctor if
you have any unusual problems while taking this medication.
Amitriptyline Hcl Drug Interactions
Amitriptyline hcl may block the antihypertensive action of guanethidine
or similarly acting compounds.When amitriptyline is given with anticholinergic
agents or sympathomimetic drugs, including epinephrine combined
with local anesthetics, close supervision and careful adjustment
of dosage are required. Paralytic ileus may occur in patients taking
tricyclic antidepressants in combination with anticholinergic-type
drugs.
Since amitriptyline hcl, in combination with anticholinergic type drugs,
may give rise to paralytic ileus, particularly in elderly or hospitalized
patients, appropriate measures should be taken if constipation occurs
in these patients.
Cimetidine is reported to reduce hepatic metabolism of certain tricyclic
antidepressants.
Caution is advised if patients receive large doses of ethchlorvynol
concurrently. Transient delirium has been reported in patients who
were treated with 1 g of ethchlorvynol and 75 to 150 mg of amitriptyline.
Amitriptyline hcl may enhance the response to alcohol and the effects
of barbiturates and other CNS depressants. Delirium has been reported
with concurrent administration of amitriptyline and disulfiram.
Amitriptyline Storage
Keep Amitriptyline hcl in the container it came in, tightly closed,
and out of reach of children. Store it at room temperature and away
from excess heat and moisture (not in the bathroom). Throw away
any medication that is outdated or no longer needed. Talk to your
pharmacist about the proper disposal of your medication.
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